Wound Healing Effects of Arnebia Densiflora Root Extracts on Rat Palatal Mucosa

OBJECTIVES The aim of this study was to investigate wound healing effects of Arnebia densiflora (Nordm.) Ledeb. root extracts on rat palatal mucosa. METHODS A 10-mm full-thickness mucosal wounds were created on midline of rats' palate by using scalpel. In the experimental groups, a ten percent extract of A. densiflora roots was topically applied once a day as ointment on the wounds. After wounding, tissue samples from palatal mucosa were harvested at 4, 7, 14 and 21 days and then evaluated histologically. RESULTS It was observed that 10% A. densiflora root extract has progressive effects on wound healing in experimental groups. CONCLUSIONS This study suggests that A. densiflora root extract could be developed as a therapeutic agent for wound healing.